Adobe FreeHand best practices for Prinergy:

Note that FreeHand will include OPI comments for TIFF only (not EPS). To perform OPI on an EPS (including DCS), create a sample of the file using an image sampler. Performing OPI on a DCS is desirable because Prinergy will recomposite the DCS on OPI into the composite page allowing you to use Prinergy trapping.