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To avoid this problem, perform the calibrations separately. After completing a successful calibration on the first monitor, quit Matchprint Virtual, re-launch Matchprint Virtual, manually bring the window to the second monitor's desktop and calibrate the second monitor.
Safari uses significant amount of memory for high-definition monitors
Safari may show a warning message - "This website is using significant memory. Closing it may improve the responsiveness of your Mac." when you continuously open heavy-contents pages in Smart Review with a high-definition monitor. You may need to (repeatedly) close and re-launch Safari.